The Nanomedicine Research Group at the
The project
combines nanoscience, polymer chemistry and synthetic
biochemistry to create polymeric nanostructures with built-in biological
building blocks to create intelligent, reactive nano-systems
that break new ground in cancer therapy. This project is funded by the Swiss
National Science Foundation and is highly competitive.
Collaborating
with polymer chemists and the biomedical researchers, the task of the PhD
student will start with expression and/or modification of bio-macromolecules
(proteins, nucleic acids), their integration into an existing polymeric targeted
nanocarrier system, their application to cell lines
and animal models of cancer, with the long-term goal of future translation to
clinical medicine.
The project
is highly interdisciplinary and is therefore only suited for a PhD student who
is able to combine excellence in his specific tasks with a broad knowledge and
the ability to work smoothly in a group, and who is willing to achieve high
goals through hard work.
The
research group combines MDs, PhDs in biomedicine, in polymer chemistry, and
in computational engineering, and also collaborates with leading groups in polymer
chemistry, cancer biology, and imaging, with the long-term goal to drive the
translation of advances in the nanosciences towards
clinical application.
If you are
interested:
-
For
informal information: send email to hunzikerp@uhbs.ch
with the keyword “PhD position” in the subject line.
-
Formal
application: also include CV, your diploma, your final
exam scores, pdf
copies of publications and research
reports written by you, a list of techniques you have used (indicate
level of
proficiency), and references or names of referees from prior
supervisors, and if you have currently no work permit in Switzerland, a
passport photocopy.
-
Optionally,
also include a 1-2 page draft proposal which delineates,
how you could combine your existing expertise in bio-macromolecule technology
with the targeted polymeric systems described in the following papers to design
a cancer therapy.
Broz P, Benito SM, Saw C, Burger P, Heider H, Pfisterer M, Marsch S, Meier W, Hunziker P.
Cell
targeting by a generic receptor-targeted polymer nanocontainer
platform
J Control Release. 2005 Feb 2;102(2):475-88.